Sunday, September 2, 2007

Clomid Resistance

When I first saw an OB/GYN to discuss why I wasn’t ovulating, she immediately suggested that I go on Clomid. She herself had taken Clomid to get pregnant, and she was sure it would work for me. This was in October 2004, and we had been trying to get pregnant for about 4 months.

I was hesitant to rush right into Clomid. I felt like it was a quick fix (ha!) that didn’t actually address the issue that I didn’t have regular cycles. I had read a little bit about how Metformin helped regulate the cycles of women with PCOS and asked my doctor if we could try that first. I wasn’t glucose intolerant, so she wouldn’t give me Metformin. It was Clomid or nothing.

In hindsight, I should have either sucked it up and taken the Clomid, or looked for another doctor. But there was a lot going on in our lives at that time. I had been looking for a job for nearly a year, and we were contemplating picking up and moving across the country (which we did 6 months later). I wasn’t ready for Clomid yet. I remember thinking, “What if she’s wrong? What if it doesn’t work? Then what?”

I finally succumbed to the allure of Clomid in the summer of 2006. My new OB/GYN had let me test drive the Metformin for a few months, and it didn’t take, so I decided it was time to give Clomid a spin. We did four Clomid cycles—I ovulated (but didn’t conceive) the first time out, and then never again. She kindly let me know that I needed the help of a reproductive endocrinologist.

My RE decided we should do a high dose of Clomid, with monitoring of my follicles by ultrasound. Again, I ovulated on our first try and again didn’t conceive, even with IUI. My subsequent Clomid cycles resulted in follicles that never got big enough to trigger ovulation. After three tries, my RE recommended that we move on to injectables.

Do I regret not going on Clomid earlier? A little. Maybe we would have figured out that it wasn’t going to work, and we’d have found success with another protocol sooner. But as I said, I just wasn’t ready yet. I was grateful to find a doctor that was willing to try the Metformin before moving on to Clomid. I think that being part of that decision made me feel a little more in control of the situation. I may have delayed the inevitable, but at least it was my choice.

4 comments:

Clomid Prescription Information said...

My name is Holly Lem and i would like to show you my personal experience with Clomid.

I am 28 years old. I got preg first time on my own & miscarried. after a while of trying, my dr put me on clomid. after the first round i got pregnant & miscarried. i decided not to try or think about it at all probably for a 9 months... right around the time baby would be due & then started trying again. after a few months got back on clomid. after 5 months and no pregnancy i'm giving it a rest again. it's to much disappointment. i'm going to give it a try again soon, in the mean time we're keeping our fingers crossed for the old fashioned way to work.

I have experienced some of these side effects-
HOT FLASHES, moody, cry easily, weight gain, headaches etc!!

I hope this information will be useful to others,
Holly Lem

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